Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_5475 |
| Peptide Name | IRT1_ARATH |
| PMID(s) | --NA-- |
| Plant Source (Scientific Name) | Arabidopsis thaliana |
| Plant Source (Common Name) | Mouse-ear cress |
| Plant Family | Brassicaceae |
| Peptide Family | --NA-- |
| Peptide Function | Signaling-peptide |
| Peptide Function Description | Alternative splicing; Complete proteome; Ion transport; Iron; Iron transport; Membrane; Signal; Transmembrane; Transport | Fe(2) transport protein 1 precursor (Fe(II) transport protein 1),(Iron-regulated transporter 1).Cell membrane; Multi-pass membrane protein. |
| Activity Against | --NA-- |
| IC50 value | --NA-- |
| Sequence | FFFAVTTPFGIALGIALSTVYQDNSPKALITVGLLNACSAGLLIYMALVDIGLSLGATSDTCTIKGLIAALCFHQMFEGMGLGGCILQAEYTNMKKFVMAILIASMIGVGAPLFSRNVSFLQPDGNIFTIIKCFASGIILGTGFMHVLPDIMPHGHGHGHGPANDVTLPIKEDDSSNAQLLRYRVIAMVLELGIIVHSVVLLAAEFMGPKLQGSIKMQFKCLIAALLGCGGMSIIAKWAMKTIFLVLIFVSFAISPATSTAPEECGSESANPCVNKAKALPLKVIAIFVSFEMLSSICLEENPWHKFPFSGFLAMLSGLITLAIDSMATSLYTSKNAVG |
| Sequence Length | 339 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 35938.74 |
| Monoisotopic Molecular Weight (Da) | 35914.64 |
| Isoelectric Point (pI) | 6.76 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | Q38856 |
| NCBI | --NA-- |
| EMBL | U27590 |
| Link to Source Databases | SPdb126177 |
|---|
| Addtional Information | FUNCTION:High-affinity iron transporter that plays a key role in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer. Acts as the principal regulator of iron homeostasis in planta. Also mediates the heavy metals uptake under iron-deficiency by its ability to transport cobalt, cadmium, manganese and/or zinc ions.ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q38856-1; Sequence=Displayed; Name=2; IsoId=Q38856-2; Sequence=VSP_008361, VSP_008362; Note=May be due to an intron retention;TISSUE SPECIFICITY:Expressed in the external cell layers of the root including the lateral branching zone. Also detected in flowers before pollination.INDUCTION:In roots by iron starvation.MISCELLANEOUS:Inhibited by cadmium and Fe(2) ions and at 100- fold excess inhibited by cobalt, manganese and zinc ions. Loss-of- function mutant exhibits a lethal chlorotic phenotype.SIMILARITY:Belongs to the ZIP transporter (TC 2.A.5) family. |
