Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_4588 |
| Peptide Name | RIP1_BRYDI |
| PMID(s) | --NA-- |
| Plant Source (Scientific Name) | Bryonia dioica |
| Plant Source (Common Name) | Red bryony |
| Plant Family | Cucurbitaceae |
| Peptide Family | --NA-- |
| Peptide Function | Signaling-peptide |
| Peptide Function Description | 3D-structure; Direct protein sequencing; Glycoprotein; Hydrolase; Plant defense; Protein synthesis inhibitor; Signal; Toxin | Ribosome-inactivating protein bryodin I precursor (EC 3.2.2.22) (rRNA,N-glycosidase) (BD1). |
| Activity Against | --NA-- |
| IC50 value | --NA-- |
| Sequence | ASARVVTSNIALLLNRNNIAAIGEDISMTLIGFEHGLYGIDVSYFFNEASATEAAKFVFKDAKKKVTLPYSGNYERLQTAAGKIRENIPLERKVYNIPLLRSSISGSGRYTLLHLTNYADETISVAVDVTNVYIMGYLAGGLPALDSAITTLYYYTASSAASALLVLIQSTAESARYKFIEQQIGKRVDKMIKLLVLWLLILTIFLKSPTVEGDVSFRLSGATTTSYGVFIKNLREALPYTFLPSLATISLENNWSALSKQIQIASTNNGQFESPVVLIDGNNQRVSITN |
| Sequence Length | 290 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 31788.51 |
| Monoisotopic Molecular Weight (Da) | 31768.85 |
| Isoelectric Point (pI) | 8.88 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | P33185 |
| NCBI | --NA-- |
| EMBL | I24020 |
| Link to Source Databases | SPdb221274 |
|---|
| Addtional Information | FUNCTION:Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.CATALYTIC ACTIVITY:Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.PTM:Appears to undergo proteolytic cleavage in the C-terminal to produce a shorter protein.BIOTECHNOLOGY:Especially useful as immunotoxin for pharmacological applications as it has low toxicity in rats and mice but is potent once inside target cells.SIMILARITY:Belongs to the ribosome-inactivating protein family.Type 1 RIP subfamily. |
