PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_4588	RIP1_BRYDI	--NA--	"Bryonia dioica"	Cucurbitaceae	--NA--	Signaling-peptide	"3D-structure; Direct protein sequencing; Glycoprotein; Hydrolase; Plant defense; Protein synthesis inhibitor; Signal; Toxin | Ribosome-inactivating protein bryodin I precursor (EC 3.2.2.22) (rRNA,N-glycosidase) (BD1)."	--NA--	ASARVVTSNIALLLNRNNIAAIGEDISMTLIGFEHGLYGIDVSYFFNEASATEAAKFVFKDAKKKVTLPYSGNYERLQTAAGKIRENIPLERKVYNIPLLRSSISGSGRYTLLHLTNYADETISVAVDVTNVYIMGYLAGGLPALDSAITTLYYYTASSAASALLVLIQSTAESARYKFIEQQIGKRVDKMIKLLVLWLLILTIFLKSPTVEGDVSFRLSGATTTSYGVFIKNLREALPYTFLPSLATISLENNWSALSKQIQIASTNNGQFESPVVLIDGNNQRVSITN	290	"Experimental evidence at protein level"	31788.51	31768.85	8.88	--NA--	"FUNCTION:Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.CATALYTIC ACTIVITY:Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.PTM:Appears to undergo proteolytic cleavage in the C-terminal to produce a shorter protein.BIOTECHNOLOGY:Especially useful as immunotoxin for pharmacological applications as it has low toxicity in rats and mice but is potent once inside target cells.SIMILARITY:Belongs to the ribosome-inactivating protein family.Type 1 RIP subfamily."