Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_3957 |
| Peptide Name | Ee-CBP (Bark) |
| PMID(s) | 15048569, 12387889, 27208129 |
| Plant Source (Scientific Name) | Euonymus europaeus |
| Plant Source (Common Name) | European spindle |
| Plant Family | Celastraceae |
| Peptide Family | Hevein |
| Peptide Function | Antibacterial, Antifungal |
| Peptide Function Description | These are identified as good candidates for development of natural additives to prevent food spoilage; Target site: lipid bilayer |
| Activity Against | Fungi: Alternaria brassicicola (IC50= 0.6 µM), Botrytis cinerea (IC50= 0.2 µM), Fusarium culmorum (IC50= 0.6 µM), Fusarium oxysporum f.sp. cubense (IC50= 3 µM), Fusarium oxysporum f.sp. matthiolae (IC50= 1 µM), Mycosphaerella eumusae (IC50= 1.2 µM), Neurospora crassa (IC50= 0.4 µM), Phoma exigua (IC50= 6.6 µM),Phytophthora cryptogea (IC50= 5 µM), Pythium ultimum (IC50= 6.6 µM), Rhizoctonia solani (IC50= 5 µM), Trichoderma hamatum (IC50= 20 µM). NOTE! Not tested against bacterial strains. |
| IC50 value | 0.6 µM | 0.2 µM | 0.6 µM | 3 µM | 1 µM | 1.2 µM | 0.4 µM | 6.6 µM | 5 µM | 6.6 µM | 5 µM | 20 µM |
| Sequence | QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG |
| Sequence Length | 45 |
| Validation | Experimental evidence at transcript level |
| Average Molecular Weight (Da) | 5019.58 |
| Monoisotopic Molecular Weight (Da) | 5016 |
| Isoelectric Point (pI) | 8.8 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | Q7Y238 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | PhytAMP_PHYT00227, CAMPSQ2948, APD_00915, DBAASP_1134 |
|---|
| Addtional Information | It contains five S-S bonds; Synthesis Type : Ribosomal|Shows 95% inhibition against (Lactobacillus brevis L1055: >40 ¼g/ml|Pediococcus dextrinicus DSM 20293: >40 ¼g/ml|Staphylococcus aureus Newman: >40 ¼g/ml|Bacillus cereus NCIMB 1526: >40 ¼g/ml|Salmonella typhimurium SL1344: >40 ¼g/ml|Escherichia coli MG1655: >40 ¼g/ml|Pseudomonas aeruginosa NCIMB 950: >40 ¼g/ml) |
