Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_2222
Peptide NameDefensin-1, Antifungal protein Psd1, Defense-related peptide 1
PMID(s)10860545, 11812144, 11697857
Plant Source (Scientific Name)Pisum sativum
Plant Source (Common Name)Garden pea
Plant FamilyFabaceae
Peptide FamilyDefensin
Peptide FunctionAntimicrobial, Antifungal
Peptide Function DescriptionTarget site: lipid bilayer, Shows antifungal activity and sodium and potassium channel inhibiting activity.
Activity AgainstAspergillus niger (IC50: 12.1 µg/ml), Aspergillus niger (IC50: 7.4 µg/ml), Aspergillus versicolor (IC50: <5.0 µg/ml), Aspergillus versicolor (IC50: 6.0 µg/ml), Fusarium moniliforme (IC50: 21.7 µg/ml), Fusarium moniliforme (IC50: 33.2 µg/ml ), Fusarium oxysporum (IC50>100 µg/ml), Fusarium oxysporum (>100 µg/ml), Fusarium solani (12.1 µg/ml), Fusarium solani (79.2 µg/ml), Neurospora crassa (0.04 µg/ml), Neurospora crassa (0.05 µg/ml), Saccharomyces cerevisiae (>100 µg/ml ), Trichophyton mentagrophytes (>100 µg/ml)
IC50 value12.1 µg/ml | 7.4 µg/ml | <5.0 µg/ml | 6.0 µg/ml | 21.7 µg/ml | 33.2 µg/ml | >100 µg/ml | >100 µg/ml | 12.1 µg/ml | 79.2 µg/ml | 0.04 µg/ml | 0.05 µg/ml | >100 µg/ml | >100 µg/ml
SequenceKTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHNWKCFCTQNC
Sequence Length46
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)5208.88
Monoisotopic Molecular Weight (Da)5205.21
Isoelectric Point (pI)7.73
Method / ExtractionNMR


Secondary Information
Tertiary Structure and DSSP ReportClick to View Structure
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_2222


External links (Uniprot, PDB and Source Information Database)
UniprotP81929, B6DX36
NCBI20139322
EMBL--NA--
Link to Source DatabasesDBAASP_782, PhytAMP_PHYT00009, EROP-Moscow_04087, DEFENSINS-Knowledgebase_96, CAMPSQ236, APD_00483
Addtional InformationSynthesis Type : Ribosomal, Experimental system used NMR, Also known as Defense-related peptide 1