This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2211 |
| Peptide Name | Kalata B7 |
| PMID(s) | 28669767, 20564013, 11535828, 17534989, 18618891, 18557620, 18295894, 18426225 |
| Plant Source (Scientific Name) | Viola hederacea, Oldenlandia affinis |
| Plant Source (Common Name) | Native Violet, Blue Diamond Flower |
| Plant Family | Violaceae, Rubiaceae |
| Peptide Family | Cyclic Peptide |
| Peptide Function | Antibacterial, Anticancer, Antifungal, Nematocide, Molluscicidal, Metal-binding, Membrane-Binding, Antiparasitic, Hemolytic, Antimicrobial |
| Peptide Function Description | Target site- Lipid Bilayer; 50% Hemolysis against Human erythrocytes at 55.2 ±1.3 µM, The Kalata B7 showed significant activity in inhibiting development of nematode larvae; shows molluscicidal activity; Kalata B7 binds to Mn2 in the presence of DPC micelles; Kalata B7 binds to DPC micelles |
| Activity Against | Escherichia coli (MBC50: 20 µM), Escherichia coli (MBC99: 40 µM), Escherichia coli (MIC: 160 µM), Escherichia coli (MIC: >160 µM), Escherichia coli (MIC: >160 µM), Escherichia coli (MIC: >160 µM), Pseudomonas aeruginosa (MBC50: 0.313 µM), Pseudomonas aeruginosa (MBC99: 0.625 µM), Pseudomonas aeruginosa (MIC: 1.25 µM), Pseudomonas aeruginosa (MIC: 160 µM), Pseudomonas aeruginosa (MIC: 160 µM), Staphylococcus aureus (MBC50: 80 µM), Staphylococcus aureus (MBC99: 160 µM), Staphylococcus aureus (MIC: >160 µM), Candida albicans (MFC50: 40 µM), Candida albicans (MFC99: 160 µM), Candida albicans (MIC: >160 µM), Human histiocytic lymphoma U-937/GTB(IC50: 29 µM) |
| IC50 value | 29 µM |
| Sequence | GLPVCGETCTLGTCYTQGCTCSWPICKRN |
| Sequence Length | 29 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 3095.6 |
| Monoisotopic Molecular Weight (Da) | 3093.33 |
| Isoelectric Point (pI) | 7.77 |
| Method / Extraction | EST, Amino acid analysis, MS, NMR |
