PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2211	"Kalata B7"	"28669767, 20564013, 11535828, 17534989, 18618891, 18557620, 18295894, 18426225"	"Viola hederacea, Oldenlandia affinis"	"Violaceae, Rubiaceae"	"Cyclic Peptide"	"Antibacterial, Anticancer, Antifungal, Nematocide, Molluscicidal, Metal-binding, Membrane-Binding, Antiparasitic, Hemolytic, Antimicrobial"	"Target site- Lipid Bilayer; 50% Hemolysis against Human erythrocytes at 55.2 ±1.3 µM, The Kalata B7 showed significant activity in inhibiting development of nematode larvae; shows molluscicidal activity; Kalata B7 binds to Mn2 in the presence of DPC micelles; Kalata B7 binds to DPC micelles"	"Escherichia coli (MBC50: 20 µM), Escherichia coli (MBC99: 40 µM), Escherichia coli (MIC: 160 µM), Escherichia coli (MIC: >160 µM), Escherichia coli (MIC: >160 µM), Escherichia coli (MIC: >160 µM), Pseudomonas aeruginosa (MBC50: 0.313 µM), Pseudomonas aeruginosa (MBC99: 0.625 µM), Pseudomonas aeruginosa (MIC: 1.25 µM), Pseudomonas aeruginosa (MIC: 160 µM), Pseudomonas aeruginosa (MIC: 160 µM), Staphylococcus aureus (MBC50: 80 µM), Staphylococcus aureus (MBC99: 160 µM), Staphylococcus aureus (MIC: >160 µM), Candida albicans (MFC50: 40 µM), Candida albicans (MFC99: 160 µM), Candida albicans (MIC: >160 µM), Human histiocytic lymphoma U-937/GTB(IC50: 29 µM)"	GLPVCGETCTLGTCYTQGCTCSWPICKRN	29	"Experimental evidence at protein level"	3095.6	3093.33	7.77	"EST, Amino acid analysis, MS, NMR"	"Synthesis Type: Ribosomal, NMR spatial structure of ternary complex Kalata B7/Mn2?? micelle (Shenkarev ZO et al J Inorg Biochem. 2008 May-Jun;102(5-6):1246-56). Divalent cation coordination is an invarint property of all cyclotides. Mn2 was found to be coordinated with E7, T8, T13, and Y15 (for details, go to the PDB). You can rotate, zoom, and view the 3D structure here in the PDB . Updated 2/2014."