Physicochemical Properties of Peptide



PPepDB ID:PPepDB_881
Number of amino acids:255
Molecular Weight:25579.29 Da
Theoretical pI:6.84


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)3814.9%
Cysteine CYS (C)155.88%
Glutamic Acid GLU (E)20.78%
Aspartic Acid ASP (D)124.71%
Glycine GLY (G)3112.16%
Phynylalanine PHE (F)83.14%
Isoleucine ILE (I)51.96%
Histidine HIS (H)41.57%
Lysine LYS (K)31.18%
Methionine MET (M)51.96%
Leucine LEU (L)197.45%
Asparagine ASN (N)62.35%
Glutamine GLN (Q)41.57%
Proline PRO (P)187.06%
Serine SER (S)2710.59%
Arginine ARG (R)114.31%
Threonine THR (T)145.49%
Tryptophan TRP (W)31.18%
Valine VAL (V)228.63%
Tyrosine TYR (Y)72.75%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):14
Total number of negatively charged residues (ASP + GLU):14
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    27805
Absorption 0.1% (=1 g/l)    1.087,   assuming all pairs of CYS residues form cystines

Ext. coefficient    26930
Absorption 0.1% (=1 g/l)    1.053,   assuming all CYS residues are reduced
Aromaticity:0.071

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 46.16

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[25.10, 32.16, 25.10]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:76.6275
Grand average of hydropathicity (GRAVY):0.00