Physicochemical Properties of Peptide



PPepDB ID:PPepDB_5195
Number of amino acids:265
Molecular Weight:27500.19 Da
Theoretical pI:10.02


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)145.28%
Cysteine CYS (C)10.38%
Glutamic Acid GLU (E)103.77%
Aspartic Acid ASP (D)134.91%
Glycine GLY (G)2910.94%
Phynylalanine PHE (F)20.75%
Isoleucine ILE (I)93.4%
Histidine HIS (H)00%
Lysine LYS (K)3212.08%
Methionine MET (M)20.75%
Leucine LEU (L)186.79%
Asparagine ASN (N)31.13%
Glutamine GLN (Q)20.75%
Proline PRO (P)10.38%
Serine SER (S)8431.7%
Arginine ARG (R)166.04%
Threonine THR (T)62.26%
Tryptophan TRP (W)00%
Valine VAL (V)103.77%
Tyrosine TYR (Y)134.91%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1153
HydrogenH1918
NitrogenN350
OxygenO420
SulphurS3

FormulaC1153H1918N350O420S3
Total Number of Atoms:3844


Total number of positively charged residues (ARG + LYS):48
Total number of negatively charged residues (ASP + GLU):23
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    19370
Absorption 0.1% (=1 g/l)    0.704,   assuming all pairs of CYS residues form cystines

Ext. coefficient    19370
Absorption 0.1% (=1 g/l)    0.704,   assuming all CYS residues are reduced
Aromaticity:0.057

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 61.45

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[19.62, 44.15, 16.60]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:55.9623
Grand average of hydropathicity (GRAVY):-0.79