Physicochemical Properties of Peptide



PPepDB ID:PPepDB_4867
Number of amino acids:224
Molecular Weight:24305.16 Da
Theoretical pI:8.17


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)167.14%
Cysteine CYS (C)83.57%
Glutamic Acid GLU (E)125.36%
Aspartic Acid ASP (D)73.13%
Glycine GLY (G)135.8%
Phynylalanine PHE (F)73.13%
Isoleucine ILE (I)146.25%
Histidine HIS (H)41.79%
Lysine LYS (K)83.57%
Methionine MET (M)62.68%
Leucine LEU (L)2310.27%
Asparagine ASN (N)62.68%
Glutamine GLN (Q)104.46%
Proline PRO (P)229.82%
Serine SER (S)198.48%
Arginine ARG (R)135.8%
Threonine THR (T)198.48%
Tryptophan TRP (W)00%
Valine VAL (V)135.8%
Tyrosine TYR (Y)41.79%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1069
HydrogenH1735
NitrogenN295
OxygenO321
SulphurS14

FormulaC1069H1735N295O321S14
Total Number of Atoms:3434


Total number of positively charged residues (ARG + LYS):21
Total number of negatively charged residues (ASP + GLU):19
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    6460
Absorption 0.1% (=1 g/l)    0.266,   assuming all pairs of CYS residues form cystines

Ext. coefficient    5960
Absorption 0.1% (=1 g/l)    0.245,   assuming all CYS residues are reduced
Aromaticity:0.049

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 43.28

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[27.23, 26.79, 25.45]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:88.393
Grand average of hydropathicity (GRAVY):-0.06