Physicochemical Properties of Peptide



PPepDB ID:PPepDB_4709
Number of amino acids:647
Molecular Weight:72105.84 Da
Theoretical pI:8.41


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)619.43%
Cysteine CYS (C)71.08%
Glutamic Acid GLU (E)264.02%
Aspartic Acid ASP (D)385.87%
Glycine GLY (G)456.96%
Phynylalanine PHE (F)233.55%
Isoleucine ILE (I)284.33%
Histidine HIS (H)152.32%
Lysine LYS (K)355.41%
Methionine MET (M)30.46%
Leucine LEU (L)548.35%
Asparagine ASN (N)335.1%
Glutamine GLN (Q)324.95%
Proline PRO (P)467.11%
Serine SER (S)396.03%
Arginine ARG (R)335.1%
Threonine THR (T)375.72%
Tryptophan TRP (W)121.85%
Valine VAL (V)416.34%
Tyrosine TYR (Y)365.56%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):68
Total number of negatively charged residues (ASP + GLU):64
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    120015
Absorption 0.1% (=1 g/l)    1.664,   assuming all pairs of CYS residues form cystines

Ext. coefficient    119640
Absorption 0.1% (=1 g/l)    1.659,   assuming all CYS residues are reduced
Aromaticity:0.110

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 35.57

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[29.98, 25.19, 22.26]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:77.2334
Grand average of hydropathicity (GRAVY):0.00