Physicochemical Properties of Peptide



PPepDB ID:PPepDB_4284
Number of amino acids:282
Molecular Weight:32236.19 Da
Theoretical pI:6.76


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)144.96%
Cysteine CYS (C)62.13%
Glutamic Acid GLU (E)51.77%
Aspartic Acid ASP (D)10.35%
Glycine GLY (G)51.77%
Phynylalanine PHE (F)113.9%
Isoleucine ILE (I)144.96%
Histidine HIS (H)82.84%
Lysine LYS (K)10.35%
Methionine MET (M)31.06%
Leucine LEU (L)207.09%
Asparagine ASN (N)72.48%
Glutamine GLN (Q)8831.21%
Proline PRO (P)4315.25%
Serine SER (S)186.38%
Arginine ARG (R)41.42%
Threonine THR (T)103.55%
Tryptophan TRP (W)00%
Valine VAL (V)144.96%
Tyrosine TYR (Y)103.55%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1432
HydrogenH2196
NitrogenN406
OxygenO428
SulphurS9

FormulaC1432H2196N406O428S9
Total Number of Atoms:4471


Total number of positively charged residues (ARG + LYS):5
Total number of negatively charged residues (ASP + GLU):6
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15275
Absorption 0.1% (=1 g/l)    0.474,   assuming all pairs of CYS residues form cystines

Ext. coefficient    14900
Absorption 0.1% (=1 g/l)    0.462,   assuming all CYS residues are reduced
Aromaticity:0.074

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 106.12

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[24.47, 25.89, 14.89]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:66.383
Grand average of hydropathicity (GRAVY):-0.82