Physicochemical Properties of Peptide



PPepDB ID:PPepDB_4212
Number of amino acids:523
Molecular Weight:56214.37 Da
Theoretical pI:8.45


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)6913.19%
Cysteine CYS (C)91.72%
Glutamic Acid GLU (E)142.68%
Aspartic Acid ASP (D)326.12%
Glycine GLY (G)5310.13%
Phynylalanine PHE (F)214.02%
Isoleucine ILE (I)71.34%
Histidine HIS (H)132.49%
Lysine LYS (K)152.87%
Methionine MET (M)163.06%
Leucine LEU (L)478.99%
Asparagine ASN (N)152.87%
Glutamine GLN (Q)112.1%
Proline PRO (P)264.97%
Serine SER (S)519.75%
Arginine ARG (R)356.69%
Threonine THR (T)214.02%
Tryptophan TRP (W)81.53%
Valine VAL (V)336.31%
Tyrosine TYR (Y)275.16%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC2487
HydrogenH3809
NitrogenN703
OxygenO741
SulphurS25

FormulaC2487H3809N703O741S25
Total Number of Atoms:7765


Total number of positively charged residues (ARG + LYS):50
Total number of negatively charged residues (ASP + GLU):46
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    84730
Absorption 0.1% (=1 g/l)    1.507,   assuming all pairs of CYS residues form cystines

Ext. coefficient    84230
Absorption 0.1% (=1 g/l)    1.498,   assuming all CYS residues are reduced
Aromaticity:0.107

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 33.66

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[27.34, 27.72, 27.92]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:71.7591
Grand average of hydropathicity (GRAVY):-0.16