Physicochemical Properties of Peptide



PPepDB ID:PPepDB_2547
Number of amino acids:38
Molecular Weight:4176.85 Da
Theoretical pI:4.41


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)25.26%
Cysteine CYS (C)615.79%
Glutamic Acid GLU (E)37.89%
Aspartic Acid ASP (D)12.63%
Glycine GLY (G)410.53%
Phynylalanine PHE (F)00%
Isoleucine ILE (I)410.53%
Histidine HIS (H)00%
Lysine LYS (K)00%
Methionine MET (M)00%
Leucine LEU (L)12.63%
Asparagine ASN (N)12.63%
Glutamine GLN (Q)37.89%
Proline PRO (P)513.16%
Serine SER (S)12.63%
Arginine ARG (R)37.89%
Threonine THR (T)00%
Tryptophan TRP (W)12.63%
Valine VAL (V)12.63%
Tyrosine TYR (Y)12.63%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):3
Total number of negatively charged residues (ASP + GLU):4
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    7365
Absorption 0.1% (=1 g/l)    1.763,   assuming all pairs of CYS residues form cystines

Ext. coefficient    6990
Absorption 0.1% (=1 g/l)    1.674,   assuming all CYS residues are reduced
Aromaticity:0.053

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 68.71

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[21.05, 28.95, 15.79]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:64.2105
Grand average of hydropathicity (GRAVY):0.00