Physicochemical Properties of Peptide



PPepDB ID:PPepDB_2545
Number of amino acids:48
Molecular Weight:5414.07 Da
Theoretical pI:5.57


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)12.08%
Cysteine CYS (C)612.5%
Glutamic Acid GLU (E)36.25%
Aspartic Acid ASP (D)24.17%
Glycine GLY (G)714.58%
Phynylalanine PHE (F)12.08%
Isoleucine ILE (I)12.08%
Histidine HIS (H)12.08%
Lysine LYS (K)36.25%
Methionine MET (M)12.08%
Leucine LEU (L)12.08%
Asparagine ASN (N)48.33%
Glutamine GLN (Q)36.25%
Proline PRO (P)24.17%
Serine SER (S)12.08%
Arginine ARG (R)24.17%
Threonine THR (T)12.08%
Tryptophan TRP (W)00%
Valine VAL (V)24.17%
Tyrosine TYR (Y)510.42%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):5
Total number of negatively charged residues (ASP + GLU):5
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    7825
Absorption 0.1% (=1 g/l)    1.445,   assuming all pairs of CYS residues form cystines

Ext. coefficient    7450
Absorption 0.1% (=1 g/l)    1.376,   assuming all CYS residues are reduced
Aromaticity:0.125

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 34.95

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[20.83, 29.17, 12.50]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:30.4166
Grand average of hydropathicity (GRAVY):0.00