Physicochemical Properties of Peptide



PPepDB ID:PPepDB_2544
Number of amino acids:48
Molecular Weight:5447.93 Da
Theoretical pI:4.54


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)12.08%
Cysteine CYS (C)714.58%
Glutamic Acid GLU (E)36.25%
Aspartic Acid ASP (D)714.58%
Glycine GLY (G)24.17%
Phynylalanine PHE (F)00%
Isoleucine ILE (I)12.08%
Histidine HIS (H)510.42%
Lysine LYS (K)12.08%
Methionine MET (M)12.08%
Leucine LEU (L)36.25%
Asparagine ASN (N)36.25%
Glutamine GLN (Q)12.08%
Proline PRO (P)00%
Serine SER (S)48.33%
Arginine ARG (R)24.17%
Threonine THR (T)36.25%
Tryptophan TRP (W)12.08%
Valine VAL (V)24.17%
Tyrosine TYR (Y)00%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):3
Total number of negatively charged residues (ASP + GLU):10
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    5875
Absorption 0.1% (=1 g/l)    1.078,   assuming all pairs of CYS residues form cystines

Ext. coefficient    5500
Absorption 0.1% (=1 g/l)    1.010,   assuming all CYS residues are reduced
Aromaticity:0.021

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 47.96

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[14.58, 18.75, 16.67]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:46.6667
Grand average of hydropathicity (GRAVY):0.00