Physicochemical Properties of Peptide



PPepDB ID:PPepDB_2525
Number of amino acids:40
Molecular Weight:3919.37 Da
Theoretical pI:5.81


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)37.5%
Cysteine CYS (C)820%
Glutamic Acid GLU (E)00%
Aspartic Acid ASP (D)00%
Glycine GLY (G)820%
Phynylalanine PHE (F)00%
Isoleucine ILE (I)00%
Histidine HIS (H)00%
Lysine LYS (K)00%
Methionine MET (M)00%
Leucine LEU (L)25%
Asparagine ASN (N)00%
Glutamine GLN (Q)410%
Proline PRO (P)12.5%
Serine SER (S)717.5%
Arginine ARG (R)12.5%
Threonine THR (T)25%
Tryptophan TRP (W)00%
Valine VAL (V)00%
Tyrosine TYR (Y)37.5%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):1
Total number of negatively charged residues (ASP + GLU):0
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    4970
Absorption 0.1% (=1 g/l)    1.268,   assuming all pairs of CYS residues form cystines

Ext. coefficient    4470
Absorption 0.1% (=1 g/l)    1.140,   assuming all CYS residues are reduced
Aromaticity:0.075

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 37.52

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[12.50, 40.00, 12.50]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:27
Grand average of hydropathicity (GRAVY):0.00