Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1434
Number of amino acids:154
Molecular Weight:16477.02 Da
Theoretical pI:8.34


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)106.49%
Cysteine CYS (C)117.14%
Glutamic Acid GLU (E)42.6%
Aspartic Acid ASP (D)53.25%
Glycine GLY (G)2516.23%
Phynylalanine PHE (F)74.55%
Isoleucine ILE (I)74.55%
Histidine HIS (H)21.3%
Lysine LYS (K)53.25%
Methionine MET (M)21.3%
Leucine LEU (L)63.9%
Asparagine ASN (N)127.79%
Glutamine GLN (Q)53.25%
Proline PRO (P)159.74%
Serine SER (S)53.25%
Arginine ARG (R)74.55%
Threonine THR (T)95.84%
Tryptophan TRP (W)74.55%
Valine VAL (V)53.25%
Tyrosine TYR (Y)31.95%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):12
Total number of negatively charged residues (ASP + GLU):9
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43595
Absorption 0.1% (=1 g/l)    2.646,   assuming all pairs of CYS residues form cystines

Ext. coefficient    42970
Absorption 0.1% (=1 g/l)    2.608,   assuming all CYS residues are reduced
Aromaticity:0.110

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 37.14

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[22.73, 37.01, 14.29]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:48.8311
Grand average of hydropathicity (GRAVY):0.00