Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1433
Number of amino acids:158
Molecular Weight:16844.4 Da
Theoretical pI:8.03


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)95.7%
Cysteine CYS (C)127.59%
Glutamic Acid GLU (E)42.53%
Aspartic Acid ASP (D)53.16%
Glycine GLY (G)2616.46%
Phynylalanine PHE (F)74.43%
Isoleucine ILE (I)74.43%
Histidine HIS (H)10.63%
Lysine LYS (K)42.53%
Methionine MET (M)21.27%
Leucine LEU (L)63.8%
Asparagine ASN (N)127.59%
Glutamine GLN (Q)74.43%
Proline PRO (P)159.49%
Serine SER (S)63.8%
Arginine ARG (R)74.43%
Threonine THR (T)106.33%
Tryptophan TRP (W)74.43%
Valine VAL (V)63.8%
Tyrosine TYR (Y)31.9%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):11
Total number of negatively charged residues (ASP + GLU):9
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43720
Absorption 0.1% (=1 g/l)    2.596,   assuming all pairs of CYS residues form cystines

Ext. coefficient    42970
Absorption 0.1% (=1 g/l)    2.551,   assuming all CYS residues are reduced
Aromaticity:0.108

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 38.09

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[22.78, 37.34, 13.29]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:48.7975
Grand average of hydropathicity (GRAVY):0.00