Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1344
Number of amino acids:255
Molecular Weight:26777.33 Da
Theoretical pI:4.6


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)207.84%
Cysteine CYS (C)176.67%
Glutamic Acid GLU (E)72.75%
Aspartic Acid ASP (D)145.49%
Glycine GLY (G)2710.59%
Phynylalanine PHE (F)135.1%
Isoleucine ILE (I)83.14%
Histidine HIS (H)10.39%
Lysine LYS (K)83.14%
Methionine MET (M)72.75%
Leucine LEU (L)187.06%
Asparagine ASN (N)93.53%
Glutamine GLN (Q)83.14%
Proline PRO (P)103.92%
Serine SER (S)3413.33%
Arginine ARG (R)62.35%
Threonine THR (T)2610.2%
Tryptophan TRP (W)31.18%
Valine VAL (V)83.14%
Tyrosine TYR (Y)93.53%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):14
Total number of negatively charged residues (ASP + GLU):21
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30910
Absorption 0.1% (=1 g/l)    1.154,   assuming all pairs of CYS residues form cystines

Ext. coefficient    29910
Absorption 0.1% (=1 g/l)    1.117,   assuming all CYS residues are reduced
Aromaticity:0.098

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 43.87

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[23.14, 31.37, 20.39]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:56.7058
Grand average of hydropathicity (GRAVY):0.00