Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1284
Number of amino acids:255
Molecular Weight:26778.25 Da
Theoretical pI:4.94


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)187.06%
Cysteine CYS (C)176.67%
Glutamic Acid GLU (E)72.75%
Aspartic Acid ASP (D)124.71%
Glycine GLY (G)3112.16%
Phynylalanine PHE (F)135.1%
Isoleucine ILE (I)124.71%
Histidine HIS (H)10.39%
Lysine LYS (K)83.14%
Methionine MET (M)41.57%
Leucine LEU (L)166.27%
Asparagine ASN (N)114.31%
Glutamine GLN (Q)72.75%
Proline PRO (P)155.88%
Serine SER (S)259.8%
Arginine ARG (R)72.75%
Threonine THR (T)239.02%
Tryptophan TRP (W)41.57%
Valine VAL (V)155.88%
Tyrosine TYR (Y)93.53%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1172
HydrogenH1796
NitrogenN308
OxygenO369
SulphurS21

FormulaC1172H1796N308O369S21
Total Number of Atoms:3666


Total number of positively charged residues (ARG + LYS):15
Total number of negatively charged residues (ASP + GLU):19
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    36410
Absorption 0.1% (=1 g/l)    1.360,   assuming all pairs of CYS residues form cystines

Ext. coefficient    35410
Absorption 0.1% (=1 g/l)    1.322,   assuming all CYS residues are reduced
Aromaticity:0.102

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 38.54

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[27.06, 32.16, 17.65]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:66.9412
Grand average of hydropathicity (GRAVY):0.05