Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1252
Number of amino acids:134
Molecular Weight:14350.68 Da
Theoretical pI:8.48


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)107.46%
Cysteine CYS (C)128.96%
Glutamic Acid GLU (E)64.48%
Aspartic Acid ASP (D)32.24%
Glycine GLY (G)107.46%
Phynylalanine PHE (F)21.49%
Isoleucine ILE (I)85.97%
Histidine HIS (H)10.75%
Lysine LYS (K)75.22%
Methionine MET (M)53.73%
Leucine LEU (L)107.46%
Asparagine ASN (N)96.72%
Glutamine GLN (Q)75.22%
Proline PRO (P)64.48%
Serine SER (S)1410.45%
Arginine ARG (R)64.48%
Threonine THR (T)53.73%
Tryptophan TRP (W)10.75%
Valine VAL (V)107.46%
Tyrosine TYR (Y)21.49%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC605
HydrogenH998
NitrogenN178
OxygenO190
SulphurS17

FormulaC605H998N178O190S17
Total Number of Atoms:1988


Total number of positively charged residues (ARG + LYS):13
Total number of negatively charged residues (ASP + GLU):9
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    9230
Absorption 0.1% (=1 g/l)    0.643,   assuming all pairs of CYS residues form cystines

Ext. coefficient    8480
Absorption 0.1% (=1 g/l)    0.591,   assuming all CYS residues are reduced
Aromaticity:0.037

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 23.53

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[24.63, 29.10, 23.13]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:81.4926
Grand average of hydropathicity (GRAVY):0.02