Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1247
Number of amino acids:255
Molecular Weight:26609.87 Da
Theoretical pI:5.07


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)228.63%
Cysteine CYS (C)155.88%
Glutamic Acid GLU (E)93.53%
Aspartic Acid ASP (D)145.49%
Glycine GLY (G)3212.55%
Phynylalanine PHE (F)114.31%
Isoleucine ILE (I)51.96%
Histidine HIS (H)00%
Lysine LYS (K)83.14%
Methionine MET (M)51.96%
Leucine LEU (L)207.84%
Asparagine ASN (N)62.35%
Glutamine GLN (Q)41.57%
Proline PRO (P)124.71%
Serine SER (S)3011.76%
Arginine ARG (R)124.71%
Threonine THR (T)239.02%
Tryptophan TRP (W)31.18%
Valine VAL (V)145.49%
Tyrosine TYR (Y)103.92%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1149
HydrogenH1784
NitrogenN312
OxygenO375
SulphurS20

FormulaC1149H1784N312O375S20
Total Number of Atoms:3640


Total number of positively charged residues (ARG + LYS):20
Total number of negatively charged residues (ASP + GLU):23
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32275
Absorption 0.1% (=1 g/l)    1.213,   assuming all pairs of CYS residues form cystines

Ext. coefficient    31400
Absorption 0.1% (=1 g/l)    1.180,   assuming all CYS residues are reduced
Aromaticity:0.094

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 49.84

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[24.71, 31.37, 21.96]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:62.7843
Grand average of hydropathicity (GRAVY):-0.05