Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1240
Number of amino acids:255
Molecular Weight:26900 Da
Theoretical pI:4.68


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)218.24%
Cysteine CYS (C)166.27%
Glutamic Acid GLU (E)103.92%
Aspartic Acid ASP (D)135.1%
Glycine GLY (G)2810.98%
Phynylalanine PHE (F)187.06%
Isoleucine ILE (I)114.31%
Histidine HIS (H)41.57%
Lysine LYS (K)62.35%
Methionine MET (M)31.18%
Leucine LEU (L)145.49%
Asparagine ASN (N)83.14%
Glutamine GLN (Q)51.96%
Proline PRO (P)135.1%
Serine SER (S)3011.76%
Arginine ARG (R)72.75%
Threonine THR (T)249.41%
Tryptophan TRP (W)31.18%
Valine VAL (V)124.71%
Tyrosine TYR (Y)93.53%


Atomic Composition:


ElementElement's AbbreviationCount
CarbonC1180
HydrogenH1770
NitrogenN306
OxygenO378
SulphurS19

FormulaC1180H1770N306O378S19
Total Number of Atoms:3653


Total number of positively charged residues (ARG + LYS):13
Total number of negatively charged residues (ASP + GLU):23
Extinction Coefficient:Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30910
Absorption 0.1% (=1 g/l)    1.149,   assuming all pairs of CYS residues form cystines

Ext. coefficient    29910
Absorption 0.1% (=1 g/l)    1.112,   assuming all CYS residues are reduced
Aromaticity:0.118

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 41.56

This indicates that the protein/peptide is unstable
Secondary Structure Fraction [Helix, Turn, Sheet]:[26.27, 30.98, 18.82]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:60.1177
Grand average of hydropathicity (GRAVY):0.02