Physicochemical Properties of Peptide



PPepDB ID:PPepDB_1207
Number of amino acids:136
Molecular Weight:14669.19 Da
Theoretical pI:4.94


Amino Acid Composition:


Amino acidAmino acid countAmino acid percentage
Alanine ALA (A)96.62%
Cysteine CYS (C)1511.03%
Glutamic Acid GLU (E)85.88%
Aspartic Acid ASP (D)96.62%
Glycine GLY (G)118.09%
Phynylalanine PHE (F)21.47%
Isoleucine ILE (I)10.74%
Histidine HIS (H)00%
Lysine LYS (K)96.62%
Methionine MET (M)53.68%
Leucine LEU (L)1712.5%
Asparagine ASN (N)85.88%
Glutamine GLN (Q)42.94%
Proline PRO (P)32.21%
Serine SER (S)107.35%
Arginine ARG (R)53.68%
Threonine THR (T)42.94%
Tryptophan TRP (W)00%
Valine VAL (V)118.09%
Tyrosine TYR (Y)42.94%


Atomic Composition:


As there is at least one ambiguous position (B, J, X or Z) in the sequence considered, the atomic composition cannot be computed.


Total number of positively charged residues (ARG + LYS):14
Total number of negatively charged residues (ASP + GLU):17
Extinction Coefficient:This protein does not contain any Tryptophan residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    6835
Absorption 0.1% (=1 g/l)    0.466,   assuming all pairs of CYS residues form cystines

Ext. coefficient    5960
Absorption 0.1% (=1 g/l)    0.406,   assuming all CYS residues are reduced
Aromaticity:0.044

Aromaticity is the calculated relative frequency of Phe+Trp+Tyr
Instability Index:The computed Instability Index (II) is : 28.01

This indicates that the protein/peptide is stable
Secondary Structure Fraction [Helix, Turn, Sheet]:[25.74, 23.53, 28.68]

Amino acids in helix: V, I, Y, F, W, L || Amino acids in turn: N, P, G, S || Amino acids in sheet: E, M, A, L
Aliphatic index:81.6912
Grand average of hydropathicity (GRAVY):0.00