Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_5262 |
| Peptide Name | ERO2_ARATH |
| PMID(s) | --NA-- |
| Plant Source (Scientific Name) | Arabidopsis thaliana |
| Plant Source (Common Name) | Mouse-ear cress |
| Plant Family | Brassicaceae |
| Peptide Family | --NA-- |
| Peptide Function | Signaling-peptide |
| Peptide Function Description | Complete proteome; Electron transport; Endoplasmic reticulum; FAD; Flavoprotein; Glycoprotein; Membrane; Oxidoreductase; Redox-active center; Signal; Transport | Endoplasmic oxidoreductin-2 precursor (EC 1.8.4.-).Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. |
| Activity Against | --NA-- |
| IC50 value | --NA-- |
| Sequence | DYLGEAEYETGNVIEDLKTKSLVKQVVSDPKTKAACPVPFDEAKLWKGQREDNLRHNLELQRNEVIALMNLLHRLSESVKYVHDMSPAAERIAGGHASSGGPELKQQLEKQFRNISAIMDCVGCEKCRLWGKLQILGLGTALKILFTVNGIASDYLLDEATNLWGQNLTLLYDRVLRYPDRVQNLYFTFLFVLRAVTKAEMAETDVGSVKGKEKGSGKRWILLIGAIAAVLLAVVVAVFLNTQNSSISEFNSFWQRIVTSIAQSKAVSGKRSQEGKPQATVDRTLDTRAFRGWTVTDNPWTSDDETDNDEMTYVNLRLNPERRYFKVKLWCDCPFWPDDGMCRLRDCSVCECPESEFPEVFKKPLSQYNPVCTGKICNCRQAEQQKYIGIVEDCCCDYETVNRLNTEVLNPLLQDLVKTPFYYTGYIGPSARRIWEAIYSENCPKHTSEGSCQEEKILYKLVSGLHSSISVH |
| Sequence Length | 472 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 53449.01 |
| Monoisotopic Molecular Weight (Da) | 53414.87 |
| Isoelectric Point (pI) | 6.09 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | Q7X9I4 |
| NCBI | --NA-- |
| EMBL | AJ551466 |
| Link to Source Databases | SPdb76327 |
|---|
| Addtional Information | FUNCTION:Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD.Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress (By similarity).COFACTOR:FAD (By similarity).SUBUNIT:May function both as a monomer and a homodimer (By similarity).PTM:N-glycosylated.SIMILARITY:Belongs to the EROs family.SEQUENCE CAUTION:Sequence=AAC79609.1; Type=Erroneous gene model prediction; |
