Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_4061 |
| Peptide Name | NICA_ARATH |
| PMID(s) | --NA-- |
| Plant Source (Scientific Name) | Arabidopsis thaliana |
| Plant Source (Common Name) | Mouse-ear cress |
| Plant Family | Brassicaceae |
| Peptide Family | --NA-- |
| Peptide Function | Signaling-peptide |
| Peptide Function Description | Alternative splicing; Complete proteome; Glycoprotein; Membrane; Notch signaling pathway; Signal; Transmembrane | Nicastrin precursor.Membrane; Single-pass type I membrane protein (Potential). |
| Activity Against | --NA-- |
| IC50 value | --NA-- |
| Sequence | AASVVARTLYILASDNKDTSNSALGSIHVNASFVEELLTCLLACEPGLSCAEFNMVMETTKAGTHNSEACLQEGTCLPLGGYSVWSSLPPISVSSSNNRKDFFTRVSTDLSFASKIGGVLVESGSNFQQKLKGFSPDKRFPQAQFSPYENFPCVRLLNLSGEIGCSNPGINKVVAPIIKLKDVKDLVQPHTILVTADEMEGITVTTLAYIGILAAKSIITKALKQDGLSGGINTFFAHKTRVSSVTNMTLDALKIAQDSLASKNIKILSADTANPGIPPSSLMAFMRKNPQTSAVVLEDFDTNFVNKFYHSHLDDLSNINSSSVVAMAMGLIRLLSIAFTLVLLSILPLHLSLADEITSIESVPDLQKLMYVAVDGNDGAWTILPQNSSDSMGMVDPVWTESNWDTLRVHVYTVQHSAYDNAVLVANLVKDYISPTNTCPGNYAGVILGEPSSKPYLGYVGDVSRFLWNFLADKTSPVVLTVASMDTASFFRDKSFGADSPISGLVALLGAVDALSRVDGISNLKKQLVFLVLTGETWGYLGSRRFLHELDLHSDAVAGLSNTSIETVLEIGSVGKVEYKWNSAASSIMWRNYNFPVYLLSESGISAVHEILSKKKMKHGTYTSDVVQKGNTTSVCSKGVCSKTDEVCIKAESNKEGTCVVSTTRYVPAYSTRLKY |
| Sequence Length | 676 |
| Validation | Experimental evidence at transcript level |
| Average Molecular Weight (Da) | 73007.42 |
| Monoisotopic Molecular Weight (Da) | 72961.18 |
| Isoelectric Point (pI) | 6.04 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | Q8GUM5 |
| NCBI | --NA-- |
| EMBL | AL353912 |
| Link to Source Databases | SPdb169534 |
|---|
| Addtional Information | FUNCTION:Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch (By similarity).SUBUNIT:Probable component of the gamma-secretase complex, a complex composed of a presenilin homodimer, nicastrin, APH1 and PEN2 (By similarity).ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=1; Comment=A number of isoforms are produced. According to EST sequences; Name=1; IsoId=Q8GUM5-1; Sequence=Displayed;SIMILARITY:Belongs to the nicastrin family.SEQUENCE CAUTION:Sequence=CAB89225.1; Type=Erroneous gene model prediction; Sequence=CAB89226.1; Type=Erroneous gene model prediction; |
