Detailed Peptide Information

This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking

Primary Information
PPepDB ID	PPepDB_3976
Peptide Name	Ib-AMP1
PMID(s)	9305910, 9454588
Plant Source (Scientific Name)	Impatiens balsamina
Plant Source (Common Name)	Garden balsam
Plant Family	Balsaminaceae
Peptide Family	Impatiens family
Peptide Function	Antibacterial, Antifungal
Peptide Function Description	plays a role in the defense of the germinating seed against microorganisms by inhibiting the growth of a range of filamentous fungi and bacteria, esprcially Gram-positive bacteria
Activity Against	Gram-positive bacteria: Bacillus subtilis (IC50= 10 µg/mL), Micrococcus luteus (IC50= 10 µg/mL), Staphylococcus aureus (IC50= 30 µg/mL), Streptococcus faecalis (IC50= 6 µg/mL). NOTE! Not active against Escherichia coli, Proteus vulgaris, Pseudomonas solanAngiotensin Converting Enzymearum. Fungi: Alternaria longipes (IC50= 3 µg/mL), Botrytis cinerea (IC50= 12 µg/mL), Cladosporium sphaerospermum (IC50= 1 µg/mL), Fusarium culmorum (IC50= 1 µg/mL), Penicillium digitatum (IC50= 3 µg/mL), Trichoderma viride (IC50= 6 µg/mL), Verticillium alboatrum (IC50= 3 µg/mL).
IC50 value	10 µg/mL | 10 µg/mL | 30 µg/mL | 6 µg/mL | 3 µg/mL | 12 µg/mL | 1 µg/mL | 1 µg/mL | 3 µg/mL | 6 µg/mL | 3 µg/mL
Sequence	QWGRRCCGWGPGRRYCVRWC
Sequence Length	20
Validation	Experimental evidence at protein level
Average Molecular Weight (Da)	2485.91
Monoisotopic Molecular Weight (Da)	2484.12
Isoelectric Point (pI)	9.88
Method / Extraction	NMR

Secondary Information
Tertiary Structure and DSSP Report	Click to View Structure
Physico-Chemical Properties of peptides	Click to View Physico-Chemical Details of PPepDB_3976

External links (Uniprot, PDB and Source Information Database)
Uniprot	O24006
NCBI	2342597
EMBL	--NA--
Link to Source Databases	PhytAMP_PHYT00265, EROP-Moscow_02313, CAMPSQ667, APD_00913
Addtional Information	The N-terminal glutamine is cyclized (pyroglutamate). It potentially contains two S-S bonds (6-16 & 7-20). The NMR study was reported (Patel SU et al 1998. Biochemistry. Jan 27;37(4):983-90). A linearized all-D amino acid mutant is also active against yeast and fungal strains (Thevissen K et al. 2005 Peptides 26: 1113-9).