Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
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| PPepDB ID | PPepDB_3849 |
| Peptide Name | Rapakinin |
| PMID(s) | 17430180, 20188776, 21129424, 12948830, 22249830 |
| Plant Source (Scientific Name) | Brassica napus |
| Plant Source (Common Name) | Rapeseed |
| Plant Family | Brassicaceae |
| Peptide Family | ACE inhibitory peptide |
| Peptide Function | ACE-inhibitor |
| Peptide Function Description | It lowers the blood pressure of spontaneously hypertensive rats (SHR) following oral administration and act as a functional food, which may be useful in the prevention and treatment of hypertension. It also shows anti-opioid activity via the activation of the PGI(2)-IP receptor system followed by the CCK-CCK(2) receptor system; Dilates mesenteric artery via the prostaglandin IP receptor followed by CCK(1) receptor |
| Activity Against | Angiotensin Converting Enzyme(IC50=28µM) |
| IC50 value | 28µM |
| Sequence | RIY |
| Sequence Length | 3 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 450.54 |
| Monoisotopic Molecular Weight (Da) | 450.26 |
| Isoelectric Point (pI) | 8.75 |
| Method / Extraction | HPLC equipped with ODS column, GPC |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | --NA-- |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | EROP-Moscow_05001, BIOPEP_7821, AHTPDB_5114, AHTPDB_4982, AHTPDB_2957, AHTPDB_4247, AHTPDB_6142, AHTPDB_1949 |
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| Addtional Information | assay: Cushman and Cheung (1971), Yamamoto and others, assay: Holmquist et al. (1979) |
