Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_3838
Peptide NameAngiotensin I-converting enzyme inhibitor, VWIS
PMID(s)23919612, 12948830, 22249830
Plant Source (Scientific Name)Brassica napus
Plant Source (Common Name)Rapeseed
Plant FamilyBrassicaceae
Peptide FamilyACE inhibitory peptide
Peptide FunctionACE-inhibitor, Antihypertensive, Enzyme-inhibitor
Peptide Function Descriptionangiotensin converting enzyme inhibitory activity: IC50 = 30 µM.; It lowers the blood pressure of spontaneously hypertensive rats (SHR) following oral administration and act as a functional food, which may be useful in the prevention and treatment of hypertension.
Activity AgainstAngiotensin Converting Enzyme(IC50=30µM)
IC50 value30 µM
SequenceVWIS
Sequence Length4
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)503.6
Monoisotopic Molecular Weight (Da)503.27
Isoelectric Point (pI)5.49
Method / ExtractionHPLC, GPC, RP-HPLC


Secondary Information
Tertiary Structure and DSSP ReportTertiary structure of this peptide is not available as the sequence length is < 5 residues
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_3838


External links (Uniprot, PDB and Source Information Database)
Uniprot--NA--
NCBI--NA--
EMBL--NA--
Link to Source DatabasesEROP-Moscow_05002, AHTPDB_4992, AHTPDB_2955, AHTPDB_4246, AHTPDB_6141, AHTPDB_1951
Addtional Informationassay: Cushman and Cheung (1971), Yamamoto and others