Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_3800 |
| Peptide Name | Rubiscolin |
| PMID(s) | 19060385, 17766012, 11741591, PPepDB_3800_ref1 |
| Plant Source (Scientific Name) | Spinacia oleracea |
| Plant Source (Common Name) | Spinach |
| Plant Family | Amaranthaceae |
| Peptide Family | Opioid |
| Peptide Function | Antihypertensive, Hypotensive, Antinociceptive, ACE-inhibitor |
| Peptide Function Description | Rubiscolin enhanced memory consolidation at an oral dose and also exerted an anxiolytic-like effect in the elevated plus-maze test after its oral administration to mice. Anxiolytic effect of rubiscolin-6 is mediated by sigma(1) and dopamine D(1) receptors downstream of delta-opioid receptor |
| Activity Against | Angiotensin Converting Enzyme(IC50=24.4 µM) |
| IC50 value | 24.4 µM |
| Sequence | YPLDLF |
| Sequence Length | 6 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 766.89 |
| Monoisotopic Molecular Weight (Da) | 766.39 |
| Isoelectric Point (pI) | 3.8 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | --NA-- |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | BIOPEP_7557, AHTPDB_6543 |
|---|
| Addtional Information | Has an analgesic effect after intracerebroventricular and oral administration via opioid receptor |
