Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_3388 |
| Peptide Name | Vulgarinin |
| PMID(s) | 15896669 |
| Plant Source (Scientific Name) | Phaseolus vulgaris |
| Plant Source (Common Name) | Kidney bean |
| Plant Family | Fabaceae |
| Peptide Family | Defensin |
| Peptide Function | Antibacterial, Antifungal, Antiviral |
| Peptide Function Description | Inhibit proliferation in leukemia cell lines L1210 and M1 and breast cancer cell line MCF-7. It reduce the activity of HIV-1 reverse transcriptase and inhibit translation in a cell-free rabbit reticulocyte lysate system. Its antifungal activity was retained after incubation with trypsin. |
| Activity Against | Botrytis cinerea (IC50= 2.9 µM), Fusarium oxysporum (IC50= 1.7 µM), Physalospora piricola (IC50= 2.2 µM), Mycosphaerella arachidicola (IC50= 0.21 µM), Mycobacterium phlei (IC50= 87 ± 5 µM), Proteus vulgaris (IC50= 75 ± 6 µM), HIV-1 reverse transcriptase (IC50= 130 µM) |
| IC50 value | 2.9 µM | 1.7 µM | 2.2 µM | 0.21 µM | 87 ± 5 µM | 75 ± 6 µM | 130 µM |
| Sequence | KTCENLADTYKGPCFTSGGD |
| Sequence Length | 20 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 2107.29 |
| Monoisotopic Molecular Weight (Da) | 2105.9 |
| Isoelectric Point (pI) | 4.56 |
| Method / Extraction | Affinity chromatography and gel filtration |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | --NA-- |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | --NA-- |
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| Addtional Information | NA |
