Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_2982
Peptide NameAngiotensin I-converting enzyme inhibitor, Rubimetide
PMID(s)18180074, 6269077, 28333109, 12903942, 28317757, 18243414, 24915368, 23598136
Plant Source (Scientific Name)Spinacia oleracea
Plant Source (Common Name)Spinach
Plant FamilyAmaranthaceae
Peptide FamilyACE inhibitory peptide
Peptide FunctionEnzyme-inhibitor, Antihypertensive, Hypotensive, Antinociceptive, ACE-inhibitor
Peptide Function Descriptioninhibits the activity of the angiotensin-converting enzyme (IC50=0.6 µM) and enhances the action of bradykinin by inhibiting the kinases that inactivate it; acts as an indirect hypotensive agent.
Activity Against--NA--
IC50 value--NA--
SequenceMRW
Sequence Length3
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)491.61
Monoisotopic Molecular Weight (Da)491.23
Isoelectric Point (pI)9.5
Method / ExtractionEnzymatic hydrolysis with pepsin-pancreatin, RP-HPLC, IEC


Secondary Information
Tertiary Structure and DSSP ReportTertiary structure of this peptide is not available as the sequence length is < 5 residues
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_2982


External links (Uniprot, PDB and Source Information Database)
UniprotP00875
NCBI--NA--
EMBL--NA--
Link to Source DatabasesEROP-Moscow_07288, AHTPDB_5124, AHTPDB_2574, AHTPDB_1923, AHTPDB_6226, AHTPDB_6229
Addtional Informationassay: Cushman and Cheung (1971), Maruyama and Suzuki