Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_276 |
| Peptide Name | Snakin-Z |
| PMID(s) | 23962183 |
| Plant Source (Scientific Name) | Ziziphus jujuba |
| Plant Source (Common Name) | Jujube |
| Plant Family | Rhamnaceae |
| Peptide Family | Snakin |
| Peptide Function | Antibacterial, Antifungal, Antioxidant, Enzyme-inhibitor |
| Peptide Function Description | Shows antimicrobial activity. Human red blood cells also shows good tolerance to the Snakin-Z. Hence it can be used for therapeutic applications. |
| Activity Against | Phomopsis azadirachtae(IC50= 7.65 µg/ml), Staphylococcus aureus(IC50= 28.8 µg/ml) |
| IC50 value | 7.65 µg/ml | 28.8 µg/ml |
| Sequence | CARLNCVPKGTSGNTETCPCYASLHSCRKYG |
| Sequence Length | 31 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 3320.8 |
| Monoisotopic Molecular Weight (Da) | 3318.48 |
| Isoelectric Point (pI) | 8.76 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | --NA-- |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | APD_02258 |
|---|
| Addtional Information | APD calculated molecular weight: 3308.823; molecular formula: C136H221N41O44S5; Wimley-White whole-residue hydrophobicity: 4.58 kcal/mol; molar extinction coefficient: 3292.5 (Cys paired) and 2980 (Cys not paired). Most similar to snakin-2 (39% similarity in sequence). Active against P. azadirachtae (MIC 7.65 ug/mL) and S. aureus (MIC 28.8 ug/ml). Snakin-Z also displayed antioxidant activity and is an enzyme inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes (Zare-Zardini H et al 2013). 8/22/2013. |
