Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_274
Peptide NameCycloviolacin Y4
PMID(s)18618891, 18081258
Plant Source (Scientific Name)Viola yedoensis
Plant Source (Common Name)Pansy
Plant FamilyViolaceae
Peptide FamilyCyclotide
Peptide FunctionAntiviral, Anti-HIV, Nematocide, Hemolytic, Antimicrobial
Peptide Function DescriptionShown to possess nematocidal, hemolytic and anti-HIV activity; Participate in the innate immune response of plants; therapeutically useful as anticancer agents and novel antimicrobial compounds in the protection of crops to the disinfection of hospital environments.
Activity AgainstHaemonchus contortus and Trichostrongylus colubriformis, HIV
IC50 value--NA--
SequenceGVPCGESCVFIPCITGVIGCSCSSNVCYLN
Sequence Length30
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)3025.55
Monoisotopic Molecular Weight (Da)3023.3
Isoelectric Point (pI)4
Method / ExtractionMS


Secondary Information
Tertiary Structure and DSSP ReportClick to View Structure
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_274


External links (Uniprot, PDB and Source Information Database)
Uniprot--NA--
NCBI--NA--
EMBL--NA--
Link to Source DatabasesAPD_01080, CAMPSQ769, Cybase_350
Addtional InformationCycloviolacins Y4 and Y5 are more hydrophobic (>50%) than cycloviolacin Y1 (33%, entry 1077), thereby more hemolytic.