Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_2212
Peptide NameCirculin-D
PMID(s)10691702
Plant Source (Scientific Name)Chassalia parvifolia
Plant Source (Common Name)--NA--
Plant FamilyRubiaceae
Peptide FamilyCyclotide
Peptide FunctionAntimicrobial, Antiviral, Anti-HIV
Peptide Function DescriptionTarget site: lipid bilayer; Circulins D inhibited the cytopathic effects of in vitro HIV-1 infection.
Activity AgainstHIV-1 (EC50: 0.050-0.275 µM)
IC50 value--NA--
SequenceKIPCGESCVWIPCVTSIFNCKCENKVCYHD
Sequence Length30
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)3420.03
Monoisotopic Molecular Weight (Da)3417.51
Isoelectric Point (pI)6.71
Method / Extraction--NA--


Secondary Information
Tertiary Structure and DSSP ReportClick to View Structure
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_2212


External links (Uniprot, PDB and Source Information Database)
UniprotP84642
NCBI76364212
EMBL--NA--
Link to Source DatabasesDBAASP_2983, PhytAMP_PHYT00147, EROP-Moscow_04090, Cybase_49, CAMPSQ765
Addtional InformationSynthesis Type : Ribosomal|Inhibition of the cytopathic effects of HIV-1 infection