Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2206 |
| Peptide Name | Flower-specific defensin / NaD1 |
| PMID(s) | 12644678, 23689717, 24015961, 27503651 |
| Plant Source (Scientific Name) | Nicotiana alata |
| Plant Source (Common Name) | Winged tobacco |
| Plant Family | Solanaceae |
| Peptide Family | Defensin |
| Peptide Function | Anticancer, Antifungal, Insecticidal |
| Peptide Function Description | may have antimicrobial activity,Target site: lipid bilayer ; This is biologically active against insect pests, which makes it a potential candidate for use in crop protection. |
| Activity Against | Cryptococcus neoformans var. grubii (IC50: 2.04 ±0.15 µM), Cryptococcus neoformans var. neoformans (IC50: 0.91 ±0.81 µM), Cryptococcus neoformans var. neoformans (IC50: 2.38 ±1.01 µM), Cryptococcus gattii (IC50: 1.45 ±0.59 µM), Cryptococcus gattii (IC50: 1.57 ±0.57 µM), Aspergillus niger (IC50: 2.1 ±0.76 µM), Aspergillus flavus (IC50: >10 µM), Candida albicans (IC50: 2.3 ±0.6 µM), Verticillium dahliae (IC50: 0.75 µM), Thielaviopsis basicola (IC50: 1 µM), Aspergillus nidulans (IC50: 0.8 µM), Puccinia coronata f.sp. avenae (IC50: 2.5 µM), Puccinia sorghi (IC50: 2 µM), Fusarium oxysporum f.sp. vasinfectum (IC50: 1.5 ±0.25 µM), Fusarium graminearum (IC50: 0.4 ±0.3 µM), Colletotrichum graminicola (IC50: 4.4 ±0.1 µM), Aspergillus parasiticus (IC50: 4.5 ±0.27 µM) |
| IC50 value | 2.04 ±0.15 µM | 0.91 ±0.81 µM | 2.38 ±1.01 µM | 1.45 ±0.59 µM | 1.57 ±0.57 µM | 2.1 ±0.76 µM | >10 µM | 2.3 ±0.6 µM | 0.75 µM | 1 µM | 0.8 µM | 2.5 µM | 2 µM | 1.5 ±0.25 µM | 0.4 ±0.3 µM | 4.4 ±0.1 µM | 4.5 ±0.27 µM |
| Sequence | RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC |
| Sequence Length | 47 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 5304.32 |
| Monoisotopic Molecular Weight (Da) | 5300.58 |
| Isoelectric Point (pI) | 9.08 |
| Method / Extraction | NMR |
