Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2196 |
| Peptide Name | Shepherin II, Antimicrobial peptide shep-GRP |
| PMID(s) | 11117262 |
| Plant Source (Scientific Name) | Capsella bursa pastoris |
| Plant Source (Common Name) | Shepherd's Purse |
| Plant Family | Brassicaceae |
| Peptide Family | Shepherin family |
| Peptide Function | Antibacterial, Antifungal |
| Peptide Function Description | Target site: lipid bilayer |
| Activity Against | Erwinia herbicola (IC50: 25 µg/ml), Escherichia coli (IC50: <2.5 µg/ml), Pseudomonas putida (IC50: <2.5 µg/ml), Pseudomonas syringae (IC50: <2.5 µg/ml), Salmonella typhimurium (IC50: 65 µg/ml), Serratia sp. (IC50: <2.5 µg/ml), Bacillus subtilis (IC50: >100 µg/ml), Staphylococcus aureus (IC50: >100 µg/ml), Streptococcus mutans (IC50: >100 µg/ml), Candida albicans (IC50: 5 µg/ml), Cryptococcus neoformans (IC50: <2.5 µg/ml), Saccharomyces cerevisiae (IC50: 3 µg/ml), Alternaria alternata (IC50: >100 µg/ml), Aspergillus flavus (IC50: 60 µg/ml), Aspergillus fumigatus (IC50: >100 µg/ml), Fusarium culmorum (IC50: 68 µg/ml) |
| IC50 value | 25 µg/ml | <2.5 µg/ml | <2.5 µg/ml | <2.5 µg/ml | 65 µg/ml | <2.5 µg/ml | >100 µg/ml | >100 µg/ml | >100 µg/ml | 5 µg/ml | <2.5 µg/ml | 3 µg/ml | >100 µg/ml | 60 µg/ml | >100 µg/ml | 68 µg/ml |
| Sequence | GYHGGHGGHGGGYNGGGGHGGHGGGYNGGGHHGGGGHG |
| Sequence Length | 38 |
| Validation | Experimental evidence at transcript level |
| Average Molecular Weight (Da) | 3259.18 |
| Monoisotopic Molecular Weight (Da) | 3257.29 |
| Isoelectric Point (pI) | 7.28 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | Q9FR52 |
| NCBI | 75172159 |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_2010, PhytAMP_PHYT00257, EROP-Moscow_02755, CAMPSQ959, APD_00512 |
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| Addtional Information | Synthesis Type : Ribosomal; Shepherin I and Shepherin II are two unique gly-rich AMPs (~65%) generated from the same precursor protein using different polypeptide regions. Due to multiple His residues, their net charge depend on pH. IN TFE, no ordered structure was found by CD. The original has been replaced. Provided by Biswajit Mishra. 9/6/2012. |
