Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2158 |
| Peptide Name | Cn-AMP1 |
| PMID(s) | 19111587 |
| Plant Source (Scientific Name) | Cocos nucifera |
| Plant Source (Common Name) | Coconut |
| Plant Family | Arecaceae |
| Peptide Family | --NA-- |
| Peptide Function | Antimicrobial, Antifungal |
| Peptide Function Description | Target site: lipid bilayer ; These show remarkable potential to contribute in the development of novel antibiotics from natural sources. |
| Activity Against | Escherichia coli (MIC: 82 µg/ml), Bacillus subtilis (MIC: 76 µg/ml), Pseudomonas aeruginosa (MIC: 79 µg/ml), Staphylococcus aureus (MIC: 80 µg/ml) |
| IC50 value | --NA-- |
| Sequence | SVAGRAQGM |
| Sequence Length | 9 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 876 |
| Monoisotopic Molecular Weight (Da) | 875.43 |
| Isoelectric Point (pI) | 9.47 |
| Method / Extraction | NMR |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | P86705 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_3225, EROP-Moscow_09001, CAMPSQ3175, APD_01342 |
|---|
| Addtional Information | Synthesis Type : Ribosomal; The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity (Silva et al. 2012). In the presence of SDS, the peptide adopted a helical structure based on both CD and NMR (Santana MJ et al., 2015). You can rotate, zoom, and view the 3D structure here in the PDB . Updated 4/2016. |
