Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2150 |
| Peptide Name | Defensin Lc-def |
| PMID(s) | 25086358, 18468512 |
| Plant Source (Scientific Name) | Lens culinaris |
| Plant Source (Common Name) | Lentil |
| Plant Family | Fabaceae |
| Peptide Family | Defensin |
| Peptide Function | Antibacterial, Antifungal |
| Peptide Function Description | Target site- Lipid Bilayer |
| Activity Against | Agrobacterium tumefaciens, Clavibacter michiganensis, Pseudomonas syringae, Alternaria alternata, Ascochyta pisi, Aspergillus niger (IC50: 18.5 µM), Aspergillus versicolor (IC50: 18.5 µM), Botrytis cinerea (IC50: 9.25 µM), Fusarium culmorum (IC50: 18.5-37.0 µM), Fusarium solani, Neurospora crassa (IC50: 9.25-18.5 µM) |
| IC50 value | 18.5 µM | 18.5 µM | 9.25 µM | 18.5-37.0 µM | 9.25-18.5 µM |
| Sequence | KTCENLSDSFKGPCIPDGNCNKHCKEKEHLLSGRCRDDFRCWCTRNC |
| Sequence Length | 47 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 5449.18 |
| Monoisotopic Molecular Weight (Da) | 5445.4 |
| Isoelectric Point (pI) | 8.2 |
| Method / Extraction | NMR |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | B3F051 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_5393, EROP-Moscow_07386, CAMPSQ3971, APD_02422 |
|---|
| Addtional Information | Synthesis Type: Ribosomal; Dimer was observed using non-reducing SDS-gel. Structure was determined by NMR. There are one helical region (residues N21-K27) and three beta strands (K1-L6, S32-C35, and C41-C47). You can rotate, zoom, and view the NMR structure 2LJ7 here in the PDB. However, no spin systems were found for residues C14-C20, probably due to micro-ms time scale motion in the loop regions, which may be involved in membrane targeting. Updated Jan2015. |
