Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
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| PPepDB ID | PPepDB_2138 |
| Peptide Name | Antimicrobial peptide EcAMP3 |
| PMID(s) | 24275143 |
| Plant Source (Scientific Name) | Echinochloa crus-galli |
| Plant Source (Common Name) | Cockspur grass |
| Plant Family | Poaceae |
| Peptide Family | Hairpin-like peptide |
| Peptide Function | Antibacterial, Antifungal |
| Peptide Function Description | Target site- Lipid Bilayer |
| Activity Against | Pseudomonas syringae (MIC: 4.5 µM), Clavibacter michiganensis subsp. michiganensis (MIC: 2.1 µM), Erwinia carotovora subsp. carotovora (MIC: 9.8 µM), Fusarium graminearum (IC50: 5.5 µM), Fusarium oxysporum(IC50: 9.6 µM), Aspergillus niger (IC50: 22.4 µM), Bipolaris sorokiniana(IC50: 15.0 µM) |
| IC50 value | 5.5 µM | 9.6 µM | 22.4 µM | 15.0 µM |
| Sequence | GADRCRERCERRHRGDWQGKQRCLMECRRREQEED |
| Sequence Length | 35 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 4434.91 |
| Monoisotopic Molecular Weight (Da) | 4432.03 |
| Isoelectric Point (pI) | 8.55 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | A0A059P9Y2, A0A059P9Y0, A0A059P9X7, V5T948, V5TAQ7, V5TA00, V5T9K0, V5TB87, V5T9Z6, V5T9J5, V5TB82, B3EWR6 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_6766, EROP-Moscow_11394, APD_02477 |
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| Addtional Information | Synthesis Type: Ribosomal, Proteins and peptides were isolated from crushed seeds by acidic extraction followed by acetone precipitation and fractionation using a variety of liquid chromatography methods. 45.9% similar to EcAMP2 isolated from the same plant. Also similar to plant EcAMP1, MBP-1, and Tk-AMP-X2. EcAMP3 is active against plant fungal pathogens, including F. graminearum (IC50 5.5 uM), F. oxysporum (IC50 9.6 uM), A. niger (IC50 22.4 uM), and B. sorokiniana (IC50 15 uM). The peptide can be cleaved by trypsin. |
