Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2098 |
| Peptide Name | Anticancerous peptide 1, Cr-ACP1 |
| PMID(s) | 21882228 |
| Plant Source (Scientific Name) | Cycas revoluta |
| Plant Source (Common Name) | Sago palm |
| Plant Family | Cycadaceae |
| Peptide Family | Anticancerous peptide 1 |
| Peptide Function | Antibacterial, Anticancer, Antifungal |
| Peptide Function Description | Target site: lipid bilayer, DNA, RNA; Used to design a novel derivative of this peptide having therapeutic potential. Human epidermoid cancer. Induce cell cycle arrest at the G0-G1 phase of Hep2 cells |
| Activity Against | Staphylococcus epidermidis (MIC: 60 µM), Bacillus subtilis (MIC: 30 µM), Pseudomonas aeruginosa (MIC: 30 µM), Escherichia coli (MIC: 30 µM), Human epidermoid cancer Hep2 (IC50: 1500 µM), Human colon adenocarcinoma HCT-15 (IC50: 1000 µM) |
| IC50 value | 1500 µM | 1000 µM |
| Sequence | AWKLFDDGV |
| Sequence Length | 9 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 1050.18 |
| Monoisotopic Molecular Weight (Da) | 1049.52 |
| Isoelectric Point (pI) | 4.21 |
| Method / Extraction | Reversed-phase liquid chromatography |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | B3EWE7 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_3238, CAMPSQ3516, APD_01805 |
|---|
| Addtional Information | Synthesis Type : Ribosomal; Acetylation reduced peptide activity against bacteria. |
