Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2036 |
| Peptide Name | Class I defensin, NaD2 |
| PMID(s) | 27503651, 24015961 |
| Plant Source (Scientific Name) | Nicotiana alata |
| Plant Source (Common Name) | Winged tobacco, Persian tobacco |
| Plant Family | Solanaceae |
| Peptide Family | Cyclotide |
| Peptide Function | Anticancer, Antifungal |
| Peptide Function Description | Target site- Lipid Bilayer |
| Activity Against | Fusarium oxysporum f.sp. vasinfectum(IC50: 8.3 ±2.1 µM), Fusarium graminearum(IC50: 2 µM), Verticillium dahliae(IC50: >10 µM), Thielaviopsis basicola(IC50: 7 µM), Aspergillus nidulans(IC50: 5 µM), Puccinia coronata f.sp. avenae(IC50: 4 µM), Puccinia sorghi(IC50: 5 µM), Human histiocytic lymphoma U-937 |
| IC50 value | 8.3 ±2.1 µM | 2 µM | >10 µM | 7 µM | 5 µM | 4 µM | 5 µM |
| Sequence | RTCESQSHRFKGPCARDSNCATVCLTEGFSGGDCRGFRRRCFCTRPC |
| Sequence Length | 47 |
| Validation | Experimental evidence at transcript level |
| Average Molecular Weight (Da) | 5263.97 |
| Monoisotopic Molecular Weight (Da) | 5260.32 |
| Isoelectric Point (pI) | 8.99 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | A0A1B2YLI5 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | DBAASP_10684 |
|---|
| Addtional Information | Synthesis Type: Ribosomal; 5.9 ±1.3% Cell death of Human histiocytic lymphoma U-937 at 10 µM |
