Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_2001 |
| Peptide Name | SFTI-1 |
| PMID(s) | 11493011, 16036912 |
| Plant Source (Scientific Name) | Helianthus annuus, Helianthus exilis, Helianthus tuberosus |
| Plant Source (Common Name) | Common sunflower, serpentine sunflower, Jerusalem artichoke |
| Plant Family | Asteraceae |
| Peptide Family | BBI-like trypsin inhibitor |
| Peptide Function | Protease-inhibitor, Enzymatic-digestion |
| Peptide Function Description | inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. |
| Activity Against | --NA-- |
| IC50 value | --NA-- |
| Sequence | GRCTKSIPPICFPD |
| Sequence Length | 14 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 1533.82 |
| Monoisotopic Molecular Weight (Da) | 1532.75 |
| Isoelectric Point (pI) | 8.06 |
| Method / Extraction | --NA-- |
| External links (Uniprot, PDB and Source Information Database) |
|---|
| Uniprot | Q4GWU5 |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | Cybase_81, EROP-Moscow_05813 |
|---|
| Addtional Information | Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity, SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity, nano-molar inhibitory effect against matriptase and trypsin, Both SFTI-1 and acyclic SFTI-1 are potent inhibitors of bovine beta trypsin, Bifunctional analogues of SFTI-1 found to be resistant to hydrolysis by trypsin |
