Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
| PPepDB ID | PPepDB_1938 |
| Peptide Name | Cycloviolacin-O1 (CYO1_VIOOD) |
| PMID(s) | 18618891, 18557620, 10600388, 12482868, 16872274, 20564013 |
| Plant Source (Scientific Name) | Viola odorata |
| Plant Source (Common Name) | Sweet violet |
| Plant Family | Violaceae |
| Peptide Family | Cyclotide |
| Peptide Function | Nematocide, Molluscicidal, Antimicrobial |
| Peptide Function Description | The cycloviolacin O1 showed significant activity in inhibiting development of nematode larvae and motility of adult worms; Cycloviolacin O1 show molluscicidal activity, 50% Hemolysis against Human erythrocytes at 61.6 ± 1.3 µM, participates in a plant defense mechanism. |
| Activity Against | Haemonchus contortus and Trichostrongylus colubriformis |
| IC50 value | --NA-- |
| Sequence | GIPCAESCVYIPCTVTALLGCSCSNRVCYN |
| Sequence Length | 30 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 3140.69 |
| Monoisotopic Molecular Weight (Da) | 3138.38 |
| Isoelectric Point (pI) | 5.96 |
| Method / Extraction | Amino acid analysis, MS, NMR |
| External links (Uniprot, PDB and Source Information Database) |
| Uniprot | P82230 |
| NCBI | 17433722 |
| EMBL | --NA-- |
| Link to Source Databases | Cybase_2, CAMPSQ6431, APD_01035, EROP-Moscow_04048, LAMP_L06AT00161, PhytAMP_PHYT00161, DBAASP_5239 |
| Addtional Information | It is toxic to Golden apple snails, serious pests of rice in South East Asia (Plan et al. 2008 J Agric Food Chem 56: 5237).You can rotate, zoom, and view the 3D structure here in the PDB . Updated 2/2014; cross link- SWISS P82230, PHYT00161 |