Detailed Peptide Information
This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking
| Primary Information |
|---|
| PPepDB ID | PPepDB_1930 |
| Peptide Name | cliotide T10 |
| PMID(s) | 26965458, 23419988 |
| Plant Source (Scientific Name) | Clitoria ternatea |
| Plant Source (Common Name) | Asian pigeonwings |
| Plant Family | Fabaceae |
| Peptide Family | Cyclotide |
| Peptide Function | Antimicrobial, Immunomodulatory, Nematocide, Anticancer |
| Peptide Function Description | Shown to possess antimicrobial activity, Target site: lipid bilayer |
| Activity Against | Human lung carcinoma A549 (IC50: 0.78 µM), Human lung carcinoma A549/paclitaxel (IC50: 1.6 µM), Caenorhabditis elegans |
| IC50 value | 0.78 µM | 1.6 µM |
| Sequence | GIPCGESCVYIPCTVTALLGCSCKDKVCYKN |
| Sequence Length | 31 |
| Validation | Experimental evidence at protein level |
| Average Molecular Weight (Da) | 3268.9 |
| Monoisotopic Molecular Weight (Da) | 3266.5 |
| Isoelectric Point (pI) | 7.76 |
| Method / Extraction | Amino acid analysis, NGS, PcR, MS |
| External links (Uniprot, PDB and Source Information Database) |
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| Uniprot | --NA-- |
| NCBI | --NA-- |
| EMBL | --NA-- |
| Link to Source Databases | Cybase_977, APD_02327, DBAASP_4281 |
|---|
| Addtional Information | May also exist as a mature linear peptide. Observed PTMs: N-terminal acetylation, hexosylation S22. (Serra et al. 2016) Highly expressed in C. ternatea root and seed. (Gilding et al. 2016) / Active against Human non-small lung cancer cells A549/ Synthesis Type : Ribosomal |
