Detailed Peptide Information


This page shows detailed information of individual peptides present in PlantPepDB database. The page is majorly divided into 3 sections. The first sections contains primary information like peptide activity, source, sequence, etc. In the secondary information section user can access the tertiary structure as well as the physico-chemical properties by clicking the respective links. Further there is also link of the source database and research article from which the peptide data is retrieved. Download the information by clicking



Primary Information
PPepDB IDPPepDB_1926
Peptide Namecycloviolacin O14
PMID(s)18618891, 18008336, 16872274
Plant Source (Scientific Name)Viola odorata
Plant Source (Common Name)Sweet violet
Plant FamilyViolaceae
Peptide FamilyCyclotide
Peptide FunctionNematocide, Anti-HIV, Hemolytic, Enzymatic-digestion, Antibacterial, Antifungal, Antiviral, Anti-HIV, Antiparasitic
Peptide Function DescriptionShowed significant activity in motility of adult worms; and also anti-HIV and hemolytic activity, participates in plant defense mechanism.
Activity AgainstHaemonchus contortus and Trichostrongylus colubriformis
IC50 value--NA--
SequenceGSIPACGESCFKGKCYTPGCSCSKYPLCAKN
Sequence Length31
ValidationExperimental evidence at protein level
Average Molecular Weight (Da)3203.74
Monoisotopic Molecular Weight (Da)3201.39
Isoelectric Point (pI)8.64
Method / ExtractionMS, Amino acid analysis, NMR


Secondary Information
Tertiary Structure and DSSP ReportClick to View Structure
Physico-Chemical Properties of peptidesClick to View Physico-Chemical Details of PPepDB_1926


External links (Uniprot, PDB and Source Information Database)
UniprotP85177
NCBI--NA--
EMBL--NA--
Link to Source DatabasesCybase_174, CAMPSQ3006, APD_01065, EROP-Moscow_07065, LAMP_L02A001065, PhytAMP_PHYT00165
Addtional InformationActive against nematode parasites of sheep (e.g. Haemonchus contortus or Trichostrongylus colubriformis). You can rotate, zoom, and view the 3D structure here in the PDB . Updated 2/2014, cross link- APD01065, PHYT00165