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The search bar provided below can be used to search for any term related to Mediator subunits. The term submitted will be looked through the whole MedProDB and list of Mediator subunits will be displayed for which the query is matched.
For example, type "ATP binding" in the text box and click on Search. A list of Mediator subunits associated with the term "ATP binding" in either MedProDB ID, Uniprot accession, name, species, functions, interaction, disease, from the database will be diplayed.
Another example would be, type "cancer" in the text box provided. A list of Mediator subunits associated with cancer will be diplayed on the next page.
Note: This search section is not specific. If you want to do a refined search, consider Simple Search, Advanced Search, or Browse section.
Mediator is a huge multisubunit complex that serves as a crucial component in the transcriptional regulation of gene expression. Mediator complex has emerged as an important regulatory component of class II gene expression and acts as an interface between the DNA bound transcription factors and RNA polymerase II.
MedProDB is the first database dedicated to Mediator protein in plants, fungi and animals. It harbors 33,971 entries of different types of Mediator subunits of various organisms. This database is believed to be beneficial for exploring the complex and rarely explored domain of Mediator proteins and its implications in all eukaryotic kingdoms. (Image source: Nucleic Acids Research, Volume 47, Issue 8, 07 May 2019, Pages 3904–3920, Figure 6)