<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33953

Description CMGC/CDK/CDK8 protein kinase
SequenceMSRSGTSLNIAQQLRKTTQLAALEDGLRGLDKKQPGNSYTSKVKIGQKYNIIGFISSGTYGRVYKAVEKNPKGDPSSPVGTSPPKELYAIKKFKPEKEGDNVQYTGLSQSAIREMSLCTELTHPNLVHLAEIILEDKCVFMVFEYCEHDLLQIIHHHTQPTRRAIPATMIKSILFQLLNGLFYLHQNWVIHRDLKPANIMVTSSGHVRIGDLGLARLFHKPLSSLYSGDKVVVTIWYRSPDLLLGARHYTPSIDLWAVGCIFAELLSLRPIFKGEETKMDSKKTVPFQRNQMGKIVEILGMPRRENWKGLVDMPEYPQLQSLIVSRGGIPGGLYPSSNSMNRGLGNNGSGLEAWYNNCLKHASYPSDKSPGQRGFQLLSELFEYDPEQRLTAEQALHHEYFRNADEGLHHGKIWVSNNCFEGLNEVYPHRRVSTETNDIGTGSLPGTKRGGLPDDSLLPAAKRR
Length464
PositionKinase
OrganismCladophialophora yegresii CBS 114405
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Cladophialophora.
Aromaticity0.08
Grand average of hydropathy-0.443
Instability index46.45
Isoelectric point9.12
Molecular weight52035.90
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33953
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.60|      12|      15|     320|     333|       1
---------------------------------------------------------------------------
  320-  333 (18.81/16.56)	QSLivSRG.GIPG.GL
  338-  351 (15.79/ 6.71)	NSM..NRGlGNNGsGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.08|      25|     199|     154|     183|       2
---------------------------------------------------------------------------
  154-  183 (33.79/36.42)	IHHHTQPTRRAiPATmiKSilFQLLNGLF.Y
  359-  384 (42.29/25.65)	LKHASYPSDKS.PGQ..RG..FQLLSELFeY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33953 with CDK8 domain of Kingdom Fungi
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