<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33935

Description U-box domain-containing protein 35
SequenceMDGSEIAESEDKFALPTPPCYVNVGIAINGRNKSKDIVRWALDKFVPEGNVIFKLIHVRPRIVAVPTAMGNFVPLSQVRDDVAAAYVKETEWQTTAILLPYKRMCAQRKVEVDVVIVESDDVANAIAAEIAKLSIKKLVIGAPSRGMFTRKLKRLSLKISARAPSFCTVYAVSKGKLSSIRPSDSETIGSSRDDNSDTRSVVSEASNASSSQTDIGSVGSGSKFRSTSLTMQRFQALATINQNLLKTRKDSVDSYHSRFQSLDLNEGKNEFGSCPSISESQASSSGSLVTDNHSWVSDQASTSDAVTDCSSLESQVNFNFEIEKLRIELRHVKGMYAMAQSETNDASRKLKDLNKQRLDEARKLEEITAEEEKAKELAIEEKEKHEAAEMEAQRLRQCTEREAALKREAETKAMHDTKEKEKLESALVGPVQQYQNFTWEEIISATSSFSEDLKIGMGGYGNIYKGNFHHTTAAVKVLHSNESHKINQFQQELEILSKIHHPHLLLLIGACPDRSCLVYEYMENGSLEDRLMQKNGTPPIPWFDRYRIAWEVASALAFLHNSKPTPIIHRDVKPANILLDHNLVSKIGDVGLAAMLQSDNSSISTMYRDTGPVGTLCYIDPEYQRTGLISPKSDVYALGMVILQLLTAKPAIALAHVVETAVADGNVMNILDPNAGNWPVEETKEFAELGLSCAELRRRDRPDLQDQVLPSLQRLKEVADKARDSASKLHFSPPPNHFICPILKDVMNDPCVAADGYTYDRKAIDKWLEVNDTSPRTNLPLPSKTLIPNYTLLSAIMERKSKEQ
Length804
PositionTail
OrganismMorus notabilis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Moraceae> Morus.
Aromaticity0.06
Grand average of hydropathy-0.405
Instability index42.27
Isoelectric point6.09
Molecular weight89353.36
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



ECO:0000256	ARBA:ARBA00003861

GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33935
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.51|      26|      28|     360|     386|       1
---------------------------------------------------------------------------
  360-  386 (36.51/28.24)	EARKLEEITaEEEKAKELAIEEKEKHE
  391-  416 (44.01/29.57)	EAQRLRQCT.EREAALKREAETKAMHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.43|      11|      27|      41|      51|       3
---------------------------------------------------------------------------
   41-   51 (19.93/10.79)	ALDKFVPEGNV
   68-   78 (20.50/11.27)	AMGNFVPLSQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.31|      23|      27|     168|     190|       4
---------------------------------------------------------------------------
  168-  190 (34.72/19.52)	T..VYAVSKGKLSSIRPSDSETIGS
  198-  220 (35.25/19.92)	T..RSVVSEASNASSSQTDIGSVGS
  272-  287 (19.88/ 8.11)	.........GSCPSISESQASSSGS
  290-  314 (32.47/17.79)	TdnHSWVSDQASTSDAVTDCSSLES
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33935 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEEEKAKELAIEEKEKHEAAEMEAQRLRQCTEREAALKREAETKAMHDTKEKEKLES
2) RPSDSETIGSSRDDNSDTRSVVSEASNASSSQTDIGS
369
181
425
217










Molecular Recognition Features






MoRF SequenceStartStop




NANANA